Selected Papers

Takashi Kohno, Mamoru Kato, Shinji Kohsaka, Tomohisa Sudo, Ikuo Tamai, Yuichi Shiraishi, Yusuke Okuma, Daisuke Ogasawara, Tatsuya Suzuki, Teruhiko Yoshida, Hiroyuki Mano
C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan
Cancer Discovery, 2022, 12, 2509-2515
Hanako Ono, Yasuhito Arai, Eisaku Furukawa, Daichi Narushima, Tetsuya Matsuura, Hiromi Nakamura, Daisuke Shiokawa, Momoko Nagai, Toshio Imai, Koshi Mimori, Koji Okamoto, Yoshitaka Hippo, Tatsuhiro Shibata, Mamoru Kato*
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model
BMC Biology, 2021, 19, 207.1-17
Iurii S. Nagornov and Mamoru Kato*
tugHall: a simulator of cancer-cell evolution based on the hallmarks of cancer and tumor-related genes
Bioinformatics, 2020, 36, 3597-3599
Mamoru Kato*, Hiromi Nakamura, Momoko Nagai, Takashi Kubo, Asmaa Elzawahry, Yasushi Totoki, Yuko Tanabe, Eisaku Furukawa, Joe Miyamoto, Hiromi Sakamoto, Shingo Matsumoto, Kuniko Sunami, Yasuhito Arai, Yutaka Suzuki, Teruhiko Yoshida, Katsuya Tsuchihara, Kenji Tamura, Noboru Yamamoto, Hitoshi Ichikawa, Takashi Kohno, and Tatsuhiro Shibata
A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing
Genome Medicine, 2018, 10, 44.1-11
Mamoru Kato*, Daniel A. Vasco, Ryuichi Sugino, Daichi Narushima, and Alexander Krasnitz
Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer
Royal Society Open Science, 2017, 4, 171060.1-11
Tsuyoshi Takahashi, Asmaa Elzawahry, Sachiyo Mimaki, Eisaku Furukawa, Rie Nakatsuka, Hiromi Nakamura, Takahiko Nishigaki, Satoshi Serada, Tetsuji Naka, Seiichi Hirota, Tatsuhiro Shibata, Katsuya Tsuchihara, Toshirou Nishida, and Mamoru Kato*
Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors
Genes, Chromosomes & Cancer, 2017, 56, 303-313

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Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, Hanako Ono, Yasuhito Arai, Fumie Hosoda, Hiroto Katoh, Kenichi Chiba, Naoko Iida, Genta Nagae, Hiroki Ueda, Chen Shihang, Shigeki Sekine, Hiroyuki Abe, Sachiyo Nomura, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Yasushi Rino, Khay Guan Yeoh, Jimmy So, Kaushal Sanghvi, Richie Soong, Akihiko Fukagawa, Shinichi Yachida, Mamoru Kato, Yasuyuki Seto, Tetsuo Ushiku, Atsushi Nakajima, Hitoshi Katai, Patrick Tan, Shumpei Ishikawa, Hiroyuki Aburatani, Tatsuhiro Shibata
Multiancestry genomic and transcriptomic analysis of gastric cancer
Nature Genetics, 2023, 55, 581-594.
Shinichi Yachida, Yasushi Totoki, Michael Noe, Yoichiro Nakatani, Masafumi Horie, Kenta Kawasaki, Hiromi Nakamura, Mihoko Saito-Adachi, Masami Suzuki, Erina Takai, Natsuko Hama, Ryota Higuchi, Seiko Hirono, Satoshi Shiba, Mamoru Kato, Eisaku Furukawa, Yasuhito Arai, Hirofumi Rokutan, Taiki Hashimoto, Shuichi Mitsunaga, Mitsuro Kanda, Hidenori Tanaka, So Takata, Ayaka Shimomura, Minoru Oshima, Wenzel M Hackeng, Tomoyuki Okumura, Keiichi Okano, Masakazu Yamamoto, Hiroki Yamaue, Chigusa Morizane, Koji Arihiro, Toru Furukawa, Toshiro Sato, Tohru Kiyono, Lodewijk A.A. Brosens, Laura D. Wood, Ralph H Hruban and Tatsuhiro Shibata
Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System
Cancer Discovery, 2021, 4, 1398–1405
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Pan-cancer analysis of whole genomes
Nature, 2020, 578, 82–93
Akihiro Fujimoto+, Mayuko Furuta+, Yasushi Totoki+, Tatsuhiko Tsunoda+, Mamoru Kato+, Yuichi Shiraishi, Hiroko Tanaka, Hiroaki Taniguchi, Yoshiiku Kawakami, Masaki Ueno, Kunihito Gotoh, Shun-ichi Ariizumi, Christopher P Wardell, Shinya Hayami, Toru Nakamura, Hiroshi Aikata, Koji Arihiro, Keith A Boroevich, Tetsuo Abe, Kaoru Nakano, Kazuhiro Maejima, Aya Sasaki-Oku, Ayako Ohsawa, Tetsuo Shibuya, Hiromi Nakamura, Natsuko Hama, Fumie Hosoda, Yasuhito Arai, Shoko Ohashi, Tomoko Urushidate, Genta Nagae, Shogo Yamamoto, Hiroki Ueda, Kenji Tatsuno, Hidenori Ojima, Nobuyuki Hiraoka, Takuji Okusaka, Michiaki Kubo, Shigeru Marubashi, Terumasa Yamada, Satoshi Hirano, Masakazu Yamamoto, Hideki Ohdan, Kazuaki Shimada, Osamu Ishikawa, Hiroki Yamaue, Kazuki Chayama, Satoru Miyano, Hiroyuki Aburatani, Tatsuhiro Shibata, and Hidewaki Nakagawa
Whole genome mutational landscape and characterization of non-coding and structural mutations in liver cancer
Nature Genetics, 2016, 48, 500-509
Shinichi Yachida, Laura D. Wood, Masami Suzuki, Erina Takai, Yasushi Totoki, Mamoru Kato, Claudio Luchini, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Asmaa Elzawahry, Fumie Hosoda, Tomoki Shirota, Nobuhiko Morimoto, Kunio Hori, Jun Funazaki, Hikaru Tanaka, Chigusa Morizane, Takuji Okusaka, Satoshi Nara, Kazuaki Shimada, Nobuyoshi Hiraoka, Hirokazu Taniguchi, Ryota Higuchi, Minoru Oshima, Keiichi Okano, Seiko Hirono, Masamichi Mizuma, Koji Arihiro, Masakazu Yamamoto, Michiaki Unno, Hiroki Yamaue, Matthew J. Weiss, Christopher L. Wolfgang, Toru Furukawa, Hitoshi Nakagama, Bert Vogelstein, Tohru Kiyono, Ralph H. Hruban, and Tatsuhiro Shibata
Genomic sequencing identifies ELF3 as a driver of ampullary carcinoma
Cancer Cell, 2016, 29, 229-240
Hiromi Nakamura, Yasuhito Arai, Yasushi Totoki, Tomoki Shirota, Asmaa Elzawahry, Mamoru Kato, Natsuko Hama, Fumie Hosoda, Tomoko Urushidate, Shoko Ohashi, Nobuyoshi Hiraoka, Hidenori Ojima, Kazuaki Shimada, Takuji Okusaka, Tomoo Kosuge, Shinichi Miyagawa, Tatsuhiro Shibata
Genomic spectra of biliary tract cancer
Nature Genetics, 2015, 47, 1003-1010
Yasushi Totoki, Kenji Tatsuno, Kyle R Covington, Hiroki Ueda, Chad J Creighton, Mamoru Kato, Shingo Tsuji, Lawrence A Donehower, Betty L Slagle, Hiromi Nakamura, Shogo Yamamoto, Eve Shinbrot, Natsuko Hama, Megan Lehmkuhl, Fumie Hosoda, Yasuhito Arai, Kim Walker, Mahmoud Dahdouli, Kengo Gotoh, Genta Nagae, Marie-Claude Gingras, Donna M Muzny, Hidenori Ojima, Kazuaki Shimada, Yutaka Midorikawa, John A Goss, Ronald Cotton, Akimasa Hayashi, Junji Shibahara, Shumpei Ishikawa, Jacfranz Guiteau, Mariko Tanaka, Tomoko Urushidate, Shoko Ohashi, Naoko Okada, Harsha Doddapaneni, Min Wang, Yiming Zhu, Huyen Dinh, Takuji Okusaka, Norihiro Kokudo, Tomoo Kosuge, Tadatoshi Takayama, Masashi Fukayama, Richard A Gibbs, David A Wheeler, Hiroyuki Aburatani, and Tatsuhiro Shibata
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
Nature Genetics, 2014, 46, 1267-1273

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Mamoru Kato, Seungtai Yoon, Naoya Hosono, Anthony Leotta, Jonathan Sebat, Tatsuhiko Tsunoda, and Michael Q. Zhang
Inferring haplotypes of copy number variations from high-throughput data with uncertainty
G3: Genes, Genomes, Genetics, 2011, the inaugural issue, 35-42
Mamoru Kato, Takahisa Kawaguchi, Shumpei Ishikawa, Takayoshi Umeda, Reiichiro Nakamichi, Michael H Shapero, Keith W Jones, Yusuke Nakamura, Hiroyuki Aburatani, and Tatsuhiko Tsunoda
Population-genetic nature of copy number variations in the human genome
Human Molecular Genetics, 2010, 19, 761-773
Mamoru Kato, Yusuke Nakamura, and Tatsuhiko Tsunoda
An algorithm for inferring complex haplotypes in a region of copy number variation
The American Journal of Human Genetics, 2008, 83, 157-169
Mamoru Kato, Yusuke Nakamura, and Tatsuhiko Tsunoda
MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data
Bioinformatics, 2008, 24, 1645-1646
Mamoru Kato, Fuyuki Miya, Yonehiro Kanemura, Toshihiro Tanaka, Yusuke Nakamura, and Tatsuhiko Tsunoda
Recombination rates of genes expressed in human tissues
Human Molecular Genetics, 2008, 17, 577-586
Mamoru Kato and Tatsuhiko Tsunoda
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
BMC Bioinformatics, 2007, 8, 100.1-9
Mamoru Kato, Akihiro Sekine, Yozo Ohnishi, Todd A. Johnson, Toshihiro Tanaka, Yusuke Nakamura, and Tatsuhiko Tsunoda
Linkage disequilibrium of evolutionarily conserved regions in the human genome
BMC Genomics, 2006, 7, 326.1-8
Mamoru Kato, Naoya Hata, Nilanjana Banerjee, Bruce Futcher, and Michael Q Zhang
Identifying combinatorial regulation of transcription factors and binding motifs
Genome Biology, 2004, 5, R56.1-13
Mamoru Kato, Tatsuhiko Tsunoda, and Toshihisa Takagi
Inferring genetic networks from DNA microarray data by multiple regression analysis
Genome Informatics, 2000, 11, 118-128